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Symbol
Name
ID
Polb
polymerase (DNA directed), beta
MGI:97740
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Anorexia
Disease(s) Associated with POLB
pancreatic cancer

Mouse Phenotypes
increased neuron apoptosis
abnormal neuron differentiation
increased trigeminal neuroma incidence
thin splanchnic nerve
small superior cervical ganglion
reduced sympathetic cervical ganglion size
abnormal brain internal capsule morphology
abnormal forebrain morphology
abnormal cerebral cortex morphology
thin cerebral cortex
abnormal hindbrain morphology
abnormal vagus ganglion morphology
small superior vagus ganglion
thin facial nerve
abnormal hypoglossal nerve topology
thin hypoglossal nerve
thin oculomotor nerve
thin motoric part of trigeminal nerve
dorsal root ganglion hyperplasia
dorsal root ganglion hypoplasia
Availability Mouse Genotype
Polbtm1.1Jbsw/Polbtm1.1Jbsw
Polbtm1a(KOMP)Wtsi/Polbtm1a(KOMP)Wtsi
Polbtm1Koy/Polbtm1Koy

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory